Batman: Arkham City

=== Characters ===

Arkham City features a large ensemble cast of characters from the history of Batman comics. Returning characters from Arkham Asylum include Batman (Kevin Conroy), the Joker (Mark Hamill)—in what Hamill stated would be his final time voicing the character; (he subsequently reprised the role in Arkham City's successor Batman: Arkham Knight)—Warden-turned-Mayor Quincy Sharp (Tom Kane), police Commissioner James Gordon (David Kaye), and reporter Jack Ryder (James Horan). Returning villains include the Riddler (Wally Wingert), Victor Zsasz (Danny Jacobs), Bane (Fred Tatasciore), and Poison Ivy (Tasia Valenza). Joker's sidekick Harley Quinn also returns, voiced by Tara Strong, who replaces Arleen Sorkin. Batman's supporting cast introduces Catwoman (Grey DeLisle), Robin (Troy Baker), and Batman's butler Alfred Pennyworth (Martin Jarvis), who provides radio support alongside the returning Oracle (Kimberly Brooks). Nightwing appears as a playable character outside of the main story via challenge maps.
Other characters marking their debut in the series include the manipulative warden of Arkham City, Hugo Strange (Corey Burton), Two-Face (also voiced by Baker), and the Penguin (Nolan North). Stana Katic lends her voice as Talia al Ghul, and Maurice LaMarche voices both Mr. Freeze and Calendar Man. Other characters include the zombie Solomon Grundy (also voiced by Tatasciore), the shapeshifter Clayface (Rick D. Wasserman), the League of Assassins's leader, Ra's al Ghul (Dee Bradley Baker), the mind-controlling Mad Hatter (Peter MacNicol), and the assassin Deadshot (Chris Cox), who has infiltrated Arkham City to kill several high-profile character targets. The villain Hush (also voiced by Conroy), the mysterious Azrael (Khary Payton), and reporter Vicki Vale (also voiced by DeLisle) also appear. Black Mask (also voiced by North), Killer Croc (Steve Blum), and Freeze's wife, Nora Fries, make cameo appearances in the game.

Setting

The events of Arkham City are set 18 months after Batman: Arkham Asylum. Quincy Sharp, the asylum's erstwhile director, has taken credit for halting the Joker's armed siege, using this distinction to become mayor of Gotham City. Declaring both the asylum and Blackgate Penitentiary no longer suitable to contain the city's detainees, Sharp's administration orders both facilities closed, and he purchases Gotham's most notorious slums and turns them into an immense prison enclosure known as Arkham City. This facility is subsequently placed in the care of psychiatrist Hugo Strange—who is secretly manipulating Sharp—and monitored by a rogue private military firm, TYGER Security. Strange permits the inmates to do as they please, so long as they do not attempt to escape. A wary Batman maintains his own vigil over the new project, afraid that the chaotic situation there will get out of hand. Meanwhile, the Joker is dying from a disease caused by his previous overdose of the Titan formula, an unstable steroid mutagen that turns men into powerful and savage monsters.

Plot

At a press conference held by Bruce Wayne to declare his opposition to Arkham City, TYGER mercenaries arrest and imprison him in the City itself. Hugo Strange discloses his knowledge of Wayne's dual identity as Batman before releasing him into the prison's criminal populace. While Strange prepares to commence "Protocol 10", Wayne obtains his equipment via airdrop from Alfred Pennyworth, allowing him to become Batman. He first saves Catwoman from being executed by Two-Face, who hopes to gain respect by murdering her. After the Joker attempts to assassinate Catwoman, Batman tracks him to his hideout in the Sionis Steelmill, believing Joker may know the truth behind Protocol 10.
There, Batman learns that the unstable properties of the Titan formula are mutating in Joker's blood, gradually killing him. Joker captures Batman and performs a blood transfusion on him, infecting him with the same fatal disease. Joker also reveals that Gotham hospitals have been poisoned with his infected blood. Desperate to save himself and innocent citizens, Batman seeks out Mr. Freeze, who has been developing a cure but has since been kidnapped by the Penguin. Tracking Penguin to his fortified museum, Batman defeats his forces, his imprisoned monster Solomon Grundy, and ultimately the Penguin himself, before liberating Mr. Freeze.
Freeze tells Batman that he has created a cure, but it is rendered useless via instability. Batman deduces that the therapeutic properties of Ra's al Ghul's blood can complete the cure and tracks one of his assassins to his underground lair, leading Batman into a confrontation with Ra's and his daughter Talia, Batman's former lover. With Ra's al Ghul's blood, Freeze is able to develop an antidote, but Harley Quinn steals it before Batman can use it.
When Batman returns to the Joker, he finds the latter's health has been restored. During a fight between the two, Strange activates Protocol 10, which is revealed to be a scheme to wipe out the entire population of Arkham City and destroy the criminal element of Gotham. TYGER troops begin executing inmates as Strange launches missile strikes on Arkham's denizens from his base in Wonder Tower. A missile hits the steel mill, burying Batman under rubble. Before Joker can take advantage of the situation, Talia arrives and offers him immortality in exchange for sparing Batman's life. After escaping with the help of Catwoman, Batman is convinced by Alfred to end Protocol 10 before pursuing Talia and Joker.
Batman infiltrates Wonder Tower and disables Protocol 10. Ra's al Ghul is revealed to be the true mastermind behind Arkham City and mortally wounds Strange for failing to defeat Batman. With his dying breath, Strange activates "Protocol 11", the self-destruction of Wonder Tower. After Ra's commits suicide to avoid capture, Joker contacts Batman, threatening to kill Talia unless Batman meets him at the Monarch Theater. When Batman arrives, Joker demands the cure from Batman but is impaled and seemingly killed by Talia while distracted. Talia admits to stealing the antidote from Quinn, before a second Joker kills her, still stricken with the disease.
The healthy Joker that Talia impaled then reanimates into the shapeshifting Clayface, who is revealed to have been masquerading as a healthy Joker all along at the ailing villain's request. During Batman's battle with Clayface, Joker blows up the theater floor, revealing that it is above the Lazarus Pit. After defeating Clayface, Batman drinks a portion of the antidote and destroys Ra's' rejuvenating Lazarus Pit before Joker can use it. As Batman debates curing his foe, Joker attacks him, inadvertently causing the antidote vial to smash. Batman admits that he would have saved him despite everything Joker had done. Joker finally succumbs to his illness and dies. Batman carries and places Joker's body on the hood of Commissioner Gordon's car before leaving Arkham City in silence.