Hades II

Chronos, the Titan of Time, returns after being overthrown by his children ages ago. He takes over the Underworld and imprisons Hades, Persephone and Zagreus while Hecate escapes with Melinoë, Zagreus' newborn baby sister, to the Crossroads in Erebus. She raises Melinoë and trains her so that she would one day exact revenge on Chronos. After her training is complete, Melinoë descends to Tartarus. Aided by blessings from the Gods of Olympus, Melinoë eventually defeats Chronos. However, Chronos employs his time powers and comes back to life, despite being repeatedly slain by Melinoë.
While looking for a way to defeat Chronos permanently, Melinoë is informed that Mount Olympus is being attacked by Chronos' army under the leadership of the Titan Prometheus, who seeks revenge against the Olympians for imprisoning him, and Typhon, the Father of All Monsters. Melinoë helps the gods defeat them, but only temporarily as they incessantly return to continue their siege. She and Hecate ultimately develop a way to slay Typhon for good and use its power to destroy Chronos permanently with assistance from a past Zagreus, with whom Melinoë manages to communicate through Nyx's Mirror.
After destroying Typhon, Melinoë creates a spell to defeat Chronos. To achieve this, she must kill him in the present while Zagreus does so in the past using Hades' spear. Melinoë defeats Chronos as planned. Instead of killing him in the past, Zagreus reasons with Chronos and makes him repent when he glimpses an alternate timeline where he lived happily with Melinoë and her family. The reformed Chronos releases Hades and the others and they restore the Underworld. Melinoë decides to return with Hecate to the Crossroads and help undo the damage Chronos caused.
After the ending, Chronos helps Melinoë confront different versions of himself and Typhon from alternate timelines to eliminate the possibility of them rising up again. In the epilogue, Melinoë is visited by the Fates, who tell her that they plan to step back from influencing events, allowing the gods to rule themselves in a "golden age" where mortals choose their own destinies.
After visiting The Fates, Melinoë speaks with Hecate and learns that she is, in fact, a version of her from an alternate timeline who successfully killed Chronos. She entered his mind with the intention of destroying him permanently, but was flung back to the beginning of time. She ingratiated herself into the House of Hades to ensure that she could train the younger, alternate version of herself to properly kill Chronos.