Marvel’s Spider-Man Remastered

=== Characters and setting ===

Marvel's Spider-Man features a large ensemble cast of characters drawn from the history of Spider-Man comics. Peter Parker (voiced by Yuri Lowenthal) is a 23-year-old research assistant, who gains superhuman abilities after being bitten by a genetically modified spider. Assuming a secret identity as the superhero Spider-Man, Peter uses these abilities to protect the residents of New York City. Eight years into his superhero career, Peter has become an experienced crime fighter but struggles to balance his superhero and personal lives. Peter is assisted by Daily Bugle reporter Mary Jane Watson (Laura Bailey), his ex-girlfriend, and NYPD captain Yuri Watanabe (Tara Platt). In his civilian life, Peter is supported by his Aunt May (Nancy Linari) who volunteers at the F.E.A.S.T. homeless shelter run by philanthropist Martin Li (Stephen Oyoung). Peter is employed by his friend and mentor, the respected scientist Dr. Otto Octavius (William Salyers).
Spider-Man's adventure brings him into contact with other characters, including Miles Morales (Nadji Jeter) and his parents, NYPD officer Jefferson Davis (Russell Richardson) and Rio Morales (Jacqueline Pinol), Oscorp CEO and New York City mayor Norman Osborn (Mark Rolston), and Silver Sable (Nichole Elise), leader of the private military company Sable International. Spider-Man's mission brings him into conflict with several supervillains, beginning with his longtime foe and Kingpin of crime in New York Wilson Fisk (Travis Willingham), and a supernaturally powered gang called the Inner Demons who begin dividing the city for Mister Negative, who can corrupt people through his touch. Spider-Man must also confront Electro (Josh Keaton), Rhino (Fred Tatasciore), Scorpion (Jason Spisak), Vulture (Dwight Schultz), Shocker (Dave B. Mitchell), Taskmaster (Brian Bloom), Screwball (Stephanie Lemelin), and Tombstone (Corey Jones).
Several other characters—including Peter and Mary Jane's childhood friend Harry Osborn (Scott Porter), who is supposed to be vacationing in Europe, and anti-Spider-Man podcast host J. Jonah Jameson (Darin De Paul)—have voice roles in the main game. Spider-Man co-creator Stan Lee appears in a cameo role as a short-order cook. The game's downloadable content features appearances by master-thief Black Cat (Erica Lindbeck), Maggia mobster Hammerhead (Keith Silverstein), and Felicia's father Walter Hardy (Daniel Riordan).
Marvel's Spider-Man depicts fictional locations and entities from the Marvel Comics universe, including Avengers Tower, the Wakandan Embassy, the Symkarian Embassy, the Sanctum Sanctorum, the law offices of Nelson and Murdock, Alias Investigations, Rand Enterprises, the superhero cleanup company Damage Control, the Roxxon Energy Corporation, and Empire State University. It also features real-world locations including the Empire State Building, One World Trade Center, Madison Square Garden, and the Chrysler Building.

Plot

Spider-Man defeats Wilson Fisk, creating a criminal power vacuum in New York City. A masked gang known as the Inner Demons begins seizing Fisk's illicit assets, and Mary Jane and Spider-Man learn that they are seeking something called Devil's Breath. With the aid of Officer Jefferson Davis, Spider-Man thwarts a Demon attack. Jefferson is lauded for his heroism at a re-election event for Mayor Norman Osborn. The Demons attack the event, killing Jefferson and many other attendees. Peter witnesses Martin Li leading the attack and appearing as “Mister Negative”, but is knocked unconscious before he can intervene. Following the attack, Norman hires Silver Sablinova and Sable International to supplant the police. Peter befriends Jefferson's son, Miles Morales, and persuades him to volunteer at F.E.A.S.T.
Peter and Otto Octavius continue their research into advanced prosthetic limbs, but Norman withdraws their funding in an attempt to force Otto to work for his mega-corporation Oscorp. While searching for Martin, Spider-Man discovers that Devil's Breath is a lethal, virulent bioweapon inadvertently created by Oscorp while developing a cure for genetic diseases. Martin steals the only sample of Devil's Breath and threatens to release it unless Norman surrenders to him. With Mary Jane’s help, Spider-Man defeats Mister Negative, who is subsequently incarcerated at nearby maximum-security prison the Raft, while the Devil's Breath is secured.
Meanwhile, Otto obsesses over creating enhanced limbs that exceed the human body's limitations, creating four mechanical tentacles operated from his back and mentally controlled via a neural interface. He reveals to Peter that he is suffering from a neuromuscular disease that will inevitably immobilize him and that enhanced limbs will allow him to continue his work when his body fails. Peter warns Otto that the interface could impact his mind and personality. Otto continues its use in secret, overcome with anger at Norman. While investigating a breakout at the Raft, Spider-Man learns that some of his greatest enemies—Martin, Electro, Vulture, Rhino, and Scorpion—have escaped. They subdue Spider-Man and present him to a crazed Otto, now "Doctor Octopus", who warns Spider-Man not to interfere before retaking the Devil's Breath and releasing it in Times Square, causing a mass outbreak that infects numerous people, including Aunt May. New York descends into chaos while Otto's team attacks the city. Norman declares martial law and blames Spider-Man for the incident, branding him a fugitive.
Spider-Man gradually takes back the city, defeating Electro, Vulture, Rhino, and Scorpion. Mary Jane infiltrates Norman's penthouse and learns that Oscorp developed Devil's Breath to cure Norman's terminally ill son Harry. As a child, Martin was a test subject for the cure, gaining his abilities in an explosion of energy that also killed his parents and caused his hatred for Norman. She also learns that an antidote for Devil's Breath exists and that Martin has stolen it. Spider-Man tracks down and defeats Martin, but Otto arrives, brutalizes Spider-Man, and escapes with the antidote and Norman. While Spider-Man recovers, Miles is bitten by an Oscorp genetically modified spider that Mary Jane unknowingly carried from Norman's penthouse.
Peter builds himself an armored “Anti-Ock” suit and confronts Otto atop Oscorp Tower, rescuing Norman. Otto reveals that he knows Peter's secret identity. Spider-Man defeats Otto and retrieves the antidote, leaving a motionless Otto to be arrested. Peter is forced to choose between using the limited cure to save May from her imminent death or synthesizing a vaccine for the infected masses; he decides to save everyone. Before she dies, May reveals that she knows he is Spider-Man and is proud of him.
Three months later, New York has returned to normal, and Peter and Mary Jane rekindle their relationship. Miles reveals to Peter that he has gained spider-like powers, prompting Peter to reveal his own. Having resigned as mayor in disgrace, Norman enters a secret laboratory where Harry is kept in stasis with a black, web-like substance. As Norman places his hand on the tank, the substance reacts and copies him.