After Piper contracts a rare fever from an illegal fruit, she slips into a coma at the hospital. Desperate to help her, Prue and Phoebe cast a spell to transfer the disease from Piper and into a doll. However, that doesn't work when the doll comes to life and starts stabbing people and as a result, the sisters have to transfer the disease back to Piper. As a result, Leo arrives and defies his orders to not interfere and ultimately saves Piper. At the Auction House, Prue decides to quit after Jack and their boss try to pass off a painting as a real Monet.
Spoilers ahead. Coverage follows the scope labeled below.
Complete story — includes the ending
When Piper contracts a life-threatening virus that sends her to intensive care, Prue and Phoebe cast an 'awakening' spell to save her life. Since the spell was used for personal gain, the sisters can no longer sleep, and Piper's sickness spreads into an epidemic as a direct consequence. Meanwhile, Prue quits her job at Buckland's and Phoebe enrolls in college. The sisters reverse the spell and Leo heals Piper against the wishes of his handlers who suspend him from his duties as a Whitelighter.