Plot summary
Years ago, Coulson and May recovered an unknown object from a Russian outpost, besting an SVR team that included Ivanov. For the failure, the SVR agents other than Ivanov were tortured and killed. Now, Ivanov sends S.H.I.E.L.D. on a treasure hunt around the world, including to that outpost, in their search for Mace. Ivanov has been torturing Mace, disgusted at his attempts to emulate the Inhumans. The team eventually finds Ivanov and Daisy overpowers him. Coulson and Mack save a near-death Mace while Fitz and Simmons attempt to locate any sign of the Framework in hopes of finding May.
Unsuccessful, the pair reunite with the others and they return to base. Aida, whom Radcliffe has left to carry out his plans while he spends time in the Framework, finds a crippled Ivanov. At base, Fitz and Simmons are alerted by their LMD security system, learning that four agents were replaced with LMDs by Aida while Fitz and Simmons were separated from the group. This includes Coulson, as the Coulson LMD wakes the May LMD from storage.
Credits
Adapted from Wikipedia contributors, Agents of S.H.I.E.L.D. season 4. HTML formatting and reference markers removed.