Plot summary
The agents on Zephyr One fight off Ivanov's men and race to the platform to save Coulson and May from Ivanov's android bodies. Ivanov launches torpedoes at the platform that threaten Mack's body, but the latter is saved by Ophelia, convinced by Fitz to put to good use the Inhuman abilities his machine gave her new body. In isolation at S.H.I.E.L.D., Fitz and Ophelia discuss her newly discovered human emotions and the fact that he remembers all the terrible things he did inside the Framework.
He admits that he ultimately still loves Simmons over her, outraging Ophelia. Glenn Talbot arrives at the ruined S.H.I.E.L.D. base, where Ophelia kills several of his soldiers and other S.H.I.E.L.D. agents, including Prince. Coulson and the others flee in the Zephyr once more, while Ophelia returns to Ivanov, who plans to use knowledge from the Darkhold to apply the changed reality of the Framework to the real world. Meanwhile, Rodriguez enters the Framework herself to try to convince Mack to leave and the Ghost Rider returns through a portal from the other dimension.
Credits
Adapted from Wikipedia contributors, Agents of S.H.I.E.L.D. season 4. HTML formatting and reference markers removed.