Plot summary
The episode opens with Quark sexually harassing one of his best waitresses. Rom rushes in to declare that, while trying to contact their mother, Ishka, he has lost contact with their home planet of Feringinar. He fears that the Dominion have taken over the planet. When they go and explain the situation to Captain Sisko, sensors pick up an incoming ship which is carrying both Grand Nagus Zek and Ishka.
The Nagus explains that by changing the Ferengi Bill of Opportunities to allow women to wear clothes, he has caused planet-wide upheaval and has been replaced by Former Liquidator Brunt who will be officially installed by the commission at its next meeting.
Quark, Rom and Nog contact all 432 of the Ferengi commissioners to come to DS9 to meet and talk about the situation. Only one commissioner agrees. Brunt finds out about the upcoming meeting and arrives on the station to torment Quark and thwart his plans. After standing up to Brunt and throwing him out of the bar, Quark and his mother return to Quark's quarters. They get into a shouting match, with Quark blaming his mother for everything that has happened to Zek, while Ishka argues that before Zek met her, he was a lonely man. The shouting match causes her to suffer a heart attack, and Dr. Bashir performs a transplant. Without Ishka to stand up and speak for herself at the meeting, Quark poses as a woman named Lumba to try and fool the commissioner.
Over dinner Quark/Lumba has to fend off the advances of the commissioner while explaining the benefits of the increase in the workforce and consumer base that Ferengi women would bring. Once in the commissioner's room, the commissioner goes into full assault, chasing Quark around the apartment. Finally Brunt bursts in and tries to unmask Lumba as an impostor and a man. This fails when "she" removes her dress, revealing her female anatomy to Brunt and the commissioner. Convinced, the commissioner pledges his support for Zek. Later Quark's sex change is reversed and Zek and Ishka leave the station anticipating Zek's restoration as Grand Nagus.
Quark, still experiencing the hormonal fluctuations from the sex change, apologizes to his mother, who accepts his apology. She tells him that while he was a lousy son, he made a wonderful daughter. After Zek and Ishka leave, Quark apologizes to the waitress he harassed at the start of the episode and gives her a raise.
Credits
Adapted from Wikipedia contributors, Profit and Lace. Paragraphs and formatting adjusted; illustrations, reference markers, block quotations and non-story material omitted.